GlobalSound

Changes to the heart linked to marathon running vary by age, sex, and training level, finds a synthesis of the available data, published in the open access journal BMJ Open Sport & Exercise Medicine.

Researchers in the del Monte Lab at the Medical University of South Carolina (MUSC) are the first to observe defects in the protein repair system associated with the peculiar, misfolded protein plaques previously observed in patients with idiopathic dilated cardiomyopathy (IDCM ).

Just two days after his minimally invasive prostate cancer treatment at NYU Langone Health, Broadway performer André De Shields, 80, was back onstage preparing for his next show, Cats: The Jellicle Ball, which debuted in April 2026.

A triple-targeted preclinical therapy combining daraxonrasib, afatinib, and SD36 drove durable pancreatic cancer regression by blocking KRAS/RAS, EGFR/HER2, and STAT3 signaling. The approach prevented treatment resistance across mouse and human tumor-derived models, but remains preclinical and requires more clinically suitable drug combinations before human testing.

MIT engineers have developed a noninvasive pacemaker that stimulates the heart using ultrasound. The design could one day provide a surgery-free alternative to traditional cardiac implants.